Title:
ヒストンデアセチラーゼ阻害剤を用いた処置のために癌患者の適性を評価する方法
Document Type and Number:
Japanese Patent JP2008532515
Kind Code:
A
Abstract:
This invention is in the field of cancer therapy and provides the use of E2F1 activity for assessing suitability of a cancer patient for treatment with histone deacetylase inhibitors (HDACIs).
Inventors:
Yuchan
Application Number:
JP2008500682A
Publication Date:
August 21, 2008
Filing Date:
March 10, 2006
Export Citation:
Assignee:
Agency for Science, Technology and Research
International Classes:
C12Q1/68; A61K45/00; A61P35/00; A61P43/00; C12N15/09; C12Q1/02; G01N33/53
Other References:
JPN6011052506; ＰＮＡＳ Ｖｏｌ．１０２， Ｎｏ．４４, 200511, ｐｐ．１６０９０-１６０９５
JPN6011052508; Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．２８１， Ｎｏ．１５, 2006, ｐｐ．１０５０８-１０５１５
JPN6011052510; Ｈｕｍａｎ Ｍｏｌｅｃｕｌａｒ Ｇｅｎｅｔｉｃｓ Ｖｏｌ．１４， Ｎｏ．１８, 200508, ｐｐ．２６４１-２６４８
JPN6011052513; Ｔｈｅ ＥＭＢＯ Ｊｏｕｒｎａｌ Ｖｏｌ．１９， Ｎｏ．４, 2000, ｐｐ．６６２-６７１
JPN6011052503; Ｉｎｔ． Ｊ． Ｃａｎｃｅｒ Ｖｏｌ．８８, 2000, ｐｐ．９９２-９９７
JPN6011052504; Ｏｎｃｏｇｅｎｅ Ｖｏｌ．２３, 2004, ｐｐ．４８０７-４８１７
JPN6011052508; Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．２８１， Ｎｏ．１５, 2006, ｐｐ．１０５０８-１０５１５
JPN6011052510; Ｈｕｍａｎ Ｍｏｌｅｃｕｌａｒ Ｇｅｎｅｔｉｃｓ Ｖｏｌ．１４， Ｎｏ．１８, 200508, ｐｐ．２６４１-２６４８
JPN6011052513; Ｔｈｅ ＥＭＢＯ Ｊｏｕｒｎａｌ Ｖｏｌ．１９， Ｎｏ．４, 2000, ｐｐ．６６２-６７１
JPN6011052503; Ｉｎｔ． Ｊ． Ｃａｎｃｅｒ Ｖｏｌ．８８, 2000, ｐｐ．９９２-９９７
JPN6011052504; Ｏｎｃｏｇｅｎｅ Ｖｏｌ．２３, 2004, ｐｐ．４８０７-４８１７
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi