Title:
自己免疫疾患及び移植片拒絶反応を治療するためのIdeSプロテイナーゼ(化膿連鎖球菌由来)の使用
Document Type and Number:
Japanese Patent JP2008542418
Kind Code:
A
Abstract:
The invention provides use of an IdeS polypeptide, or a polynucleotide encoding an IdeS polypeptide, in the manufacture of a medicament for the treatment or prevention of a disease or condition mediated by IgG antibodies.
Inventors:
Björk, Rals
Holmdal, Ricardo
Nandakumar, Cutie, Selva
Holmdal, Ricardo
Nandakumar, Cutie, Selva
Application Number:
JP2008515137A
Publication Date:
November 27, 2008
Filing Date:
June 08, 2006
Export Citation:
Assignee:
Hansa Medical Activola Get
International Classes:
A61K38/00; A61K48/00; A61P1/04; A61P1/16; A61P3/10; A61P7/04; A61P7/06; A61P17/00; A61P17/06; A61P19/02; A61P21/04; A61P27/02; A61P29/00; A61P37/06; C12N9/52; C12N15/09
Other References:
JPN6011057813; Ｔｈｅ ＥＭＢＯ Ｊｏｕｒｎａｌ Ｖｏｌ．２１， Ｎｏ．７, 2002, ｐ．１６０７-１６１５
JPN6011057815; Ｃｌｉｎｉｃａｌ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｒｈｅｕｍａｔｏｌｏｇｙ Ｖｏｌ．１１， Ｎｏ．２, 1993, ｐ．１２９-１３４
JPN6011057816; Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．３３， Ｎｏ．８, 2003, ｐ．２２６９-２２７７
JPN6011057818; Ｘｅｎｏｔｒａｎｓｐｌａｎｔａｔｉｏｎ Ｖｏｌ．６， Ｎｏ．２, 1999, ｐ．１１０-１１６
JPN6011057813; Ｔｈｅ ＥＭＢＯ Ｊｏｕｒｎａｌ Ｖｏｌ．２１， Ｎｏ．７, 2002, ｐ．１６０７-１６１５
JPN6011057815; Ｃｌｉｎｉｃａｌ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｒｈｅｕｍａｔｏｌｏｇｙ Ｖｏｌ．１１， Ｎｏ．２, 1993, ｐ．１２９-１３４
JPN6011057816; Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．３３， Ｎｏ．８, 2003, ｐ．２２６９-２２７７
JPN6011057818; Ｘｅｎｏｔｒａｎｓｐｌａｎｔａｔｉｏｎ Ｖｏｌ．６， Ｎｏ．２, 1999, ｐ．１１０-１１６
JPN6011057815; Ｃｌｉｎｉｃａｌ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｒｈｅｕｍａｔｏｌｏｇｙ Ｖｏｌ．１１， Ｎｏ．２, 1993, ｐ．１２９-１３４
JPN6011057816; Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．３３， Ｎｏ．８, 2003, ｐ．２２６９-２２７７
JPN6011057818; Ｘｅｎｏｔｒａｎｓｐｌａｎｔａｔｉｏｎ Ｖｏｌ．６， Ｎｏ．２, 1999, ｐ．１１０-１１６
JPN6011057813; Ｔｈｅ ＥＭＢＯ Ｊｏｕｒｎａｌ Ｖｏｌ．２１， Ｎｏ．７, 2002, ｐ．１６０７-１６１５
JPN6011057815; Ｃｌｉｎｉｃａｌ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｒｈｅｕｍａｔｏｌｏｇｙ Ｖｏｌ．１１， Ｎｏ．２, 1993, ｐ．１２９-１３４
JPN6011057816; Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．３３， Ｎｏ．８, 2003, ｐ．２２６９-２２７７
JPN6011057818; Ｘｅｎｏｔｒａｎｓｐｌａｎｔａｔｉｏｎ Ｖｏｌ．６， Ｎｏ．２, 1999, ｐ．１１０-１１６
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio