Title:
(R)-(-)-2-[5-(4-フルオロフェニル)-3-ピリジルメチルアミノメチル]クロマンを含有する固体医薬組成物
Document Type and Number:
Japanese Patent JP2008543894
Kind Code:
A
Abstract:
The invention relates to a solid pharmaceutical preparation containing (R)-(−)-2-[5-(4-fluorophenyl-3-pyridylmethylaminomethyl]chroman as an active substance and at least one sugar alcohol (e.g. mannitol, sorbitol) as a filler. Also disclosed is the production of said solid pharmaceutical preparation, which is provided with an increased shelf life also at elevated temperatures and can be used for the treatment of dyskinesia associated with Parkinson's disease.
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Inventors:
Knus, Claus
Heil, Kirsten
Roup, Roland
Heil, Kirsten
Roup, Roland
Application Number:
JP2008517367A
Publication Date:
December 04, 2008
Filing Date:
June 09, 2006
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
A61K31/4433; A61K9/16; A61K9/20; A61K9/48; A61K47/10; A61K47/38; A61P25/16; A61P43/00
Domestic Patent References:
| JP2002503686A | 2002-02-05 | |||
| JPH1053529A | 1998-02-24 | |||
| JPH11189547A | 1999-07-13 | |||
| JP2004536021A | 2004-12-02 | |||
| JPH10203971A | 1998-08-04 | |||
| JPH11243907A | 1999-09-14 | |||
| JP2002104956A | 2002-04-10 |
Foreign References:
| WO2001068063A2 | 2001-09-20 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Youichi Inoue
Noriki Mitsuhashi
Takakawara Yoshiko
Youichi Inoue
Noriki Mitsuhashi
Takakawara Yoshiko