Title:
3,7-ジアザ-ビシクロ[3.3.1]ノナン化合物の製造方法
Document Type and Number:
Japanese Patent JP2008546657
Kind Code:
A
Abstract:
The present invention relates to a process for the preparation of 3,7-diazabicyclo[3.3.1]nonane compounds. According to the invention, in a first step, a dicarboxylic acid ester is reacted with a pyridine aldehyde and a primary amine. The piperidone which forms is reacted in a second stage with formaldehyde and a further primary amine. It is essential to the invention that, in the first reaction stage, a C2-C4-alcohol is used as solvent and, in the second reaction stage, a C3-C4-alcohol is used as solvent.
Inventors:
Ducker Barbara
Wesling Michael
Nichuke Nicolet
Wesling Michael
Nichuke Nicolet
Application Number:
JP2008516201A
Publication Date:
December 25, 2008
Filing Date:
June 10, 2006
Export Citation:
Assignee:
Clariant Produkte (Deutschland) Gesellschaft Mito Beschlenktel Haftung
International Classes:
C07D471/08
Foreign References:
| WO2002048301A1 | 2002-06-20 |
Attorney, Agent or Firm:
Mitsufumi Esaki
Okumura Yoshimichi
Blacksmith
Okumura Yoshimichi
Blacksmith