補体C3a由来のペプチド及びその使用 - YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

Title:

補体C3a由来のペプチド及びその使用

Document Type and Number:

Japanese Patent JP2009502904

Kind Code:

A

Abstract:

Peptides corresponding partially to positions 55-64 of the sequence of the complement component peptide C3a are capable of preventing and treating mast cell- and basophil-mediated disorders by inhibiting IgE- or IgG-mediated triggering and/or by inhibiting the FcepsilonRI- and/or FcgammaR-induced secretory response, while obviating the anaphylatoxic response. These peptides are useful for prevention and/or treatment of allergic disorders where mucosal-type and/or serosal-type mast cells and/or basophils are involved such as asthma, allergic dermatosis, and gastrointestinal allergies.

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Inventors:

Pect, israel
Eldy, Anna

Application Number:

JP2008523542A

Publication Date:

January 29, 2009

Filing Date:

July 27, 2006

Export Citation:

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Assignee:

YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED

International Classes:

C07K14/47; A61K38/00; A61P1/00; A61P1/02; A61P1/06; A61P1/08; A61P1/12; A61P11/00; A61P11/06; A61P15/00; A61P17/00; A61P27/14; A61P27/16; A61P37/08; C07K7/06

Attorney, Agent or Firm:

Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio

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