Title:
T細胞免疫を調節するためのジアステレオマーペプチド
Document Type and Number:
Japanese Patent JP2009508937
Kind Code:
A
Abstract:
The present invention provides diastereomeric peptides derived from the T Cell Receptor alpha Transmembrane Domain, and lipophilic conjugates thereof, which peptides and conjugates are effective in preventing or treating T cell mediated inflammatory diseases. The invention provides pharmaceutical compositions comprising these diastereomeric peptides and conjugates, and uses thereof for therapy of inflammatory diseases, autoimmunity and graft rejection.
Inventors:
Shy, yesiel
Cohen, Irun, Earl
Quintana, Francisco
Gerber, Delon
Cohen, Irun, Earl
Quintana, Francisco
Gerber, Delon
Application Number:
JP2008531886A
Publication Date:
March 05, 2009
Filing Date:
September 21, 2006
Export Citation:
Assignee:
YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED
International Classes:
C07K14/725; A61K38/00; A61P1/04; A61P1/16; A61P3/10; A61P7/04; A61P7/06; A61P13/12; A61P17/00; A61P17/06; A61P17/14; A61P21/04; A61P25/00; A61P29/00; A61P37/02; A61P37/04; A61P37/06; C07K7/06; C12N15/09
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio