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Title:
リソフィリン類縁体とその使用方法
Document Type and Number:
Japanese Patent JP2009509926
Kind Code:
A
Abstract:
The present invention provides analogs of a Lysofylline (LSF), and synthetic methods for the preparation of such analogs. The have the active side chain moiety (5-R-hydroxyhexyl) of LSF and can have greater potency and oral bioavailability than LSF.

Inventors:
McDonald's, Timothy, Elle.
Nadler, Jerry, Elle.
Qui pen
Application Number:
JP2008529208A
Publication Date:
March 12, 2009
Filing Date:
August 29, 2006
Export Citation:
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Assignee:
UNIVERSITY OF VIRGINIA PATENT FOUNDATION
International Classes:
C07D209/08; A61K31/404; A61K31/4196; A61K31/4965; A61K31/502; A61K31/53; A61K31/538; A61P1/00; A61P3/04; A61P3/10; A61P9/10; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P29/00; C07D219/10; C07D223/26; C07D223/28; C07D237/32; C07D241/08; C07D249/12; C07D265/36; C07D265/38; C07D487/04
Domestic Patent References:
JP2004519480A2004-07-02
JP2002543135A2002-12-17
JPH10237066A1998-09-08
JP2004519480A2004-07-02
JP2002543135A2002-12-17
JPH10237066A1998-09-08
Foreign References:
WO1999036073A11999-07-22
WO1999036073A11999-07-22
Other References:
JPN6012008839; Bioorganic & Medicinal Chemistry Letters Vol.16, 2006, p.3401-3405
JPN6012008839; Bioorganic & Medicinal Chemistry Letters Vol.16, 2006, p.3401-3405
Attorney, Agent or Firm:
Yoshiyuki Osuga