Title:
スルファモイルスルホネートプロドラッグ
Document Type and Number:
Japanese Patent JP2009517424
Kind Code:
A
Abstract:
Sulfamoylsulfonate prodrugs (I) are new. Sulfamoylsulfonate prodrugs of formula (I) are new. Drug-O-SO 2-X-SO 2NH 2 (I) X : 1-12C alkanediyl, 1-5C perfluoroalkylene, 3-8C cyloalkanediyl, arylene, heteroalkanediyl, 1-4C alkanediylaryl, (1-4C)alkanediyl(3-8C)cycloalkyl or (3-8C)cycloalkanediyl(1-4C)alkyl; Drug : a pharmaceutical agent capable of forming a sulfonate through an OH group. Independent claims are also included for: (1) pharmaceutical composition comprising a prodrug (I) and another active agent; (2) a process for preparing (I). ACTIVITY : Antiparasitic; Protozoacide; Gynecological; Cytostatic; Antiinflammatory; Antiallergic. MECHANISM OF ACTION : None given.
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Inventors:
Burba, Ralph
Nubemaier, Reinhard
Gunzer, Ursula
Nubemaier, Reinhard
Gunzer, Ursula
Application Number:
JP2008542678A
Publication Date:
April 30, 2009
Filing Date:
November 27, 2006
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
A61K47/48; A61K31/4709; A61K31/565; A61K31/5685; A61K31/7064; A61K38/00; A61P15/08; A61P29/00; A61P35/00; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima