Title:
異常細胞増殖を治療するためのピリミジン誘導体
Document Type and Number:
Japanese Patent JP2009520807
Kind Code:
A
Abstract:
The present invention relates to a compound of the formula 1 or a pharmaceutically acceptable salt thereof, wherein Ar is a group of formula and R1, R2, R13, A, K, M, L1, L2, X, Y1, Y2, Q, salt thereof, wherein R1, R2, R13, A, K, L1, L2, W, X, Z1, Z2, Y1, Y2, Z1, Z2, M, Q, W, X, m, p and q are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
Inventors:
Joel Thomas Archery
Summit Kumar Buhatta Chaya
Arthur Douglas Brosius
Michael joseph ruzzio
Kendra Louise Nelson
Gonghua bread
James Alfred Suthers, Jr.
Don Gregory Wishka
Jun Xiao
Summit Kumar Buhatta Chaya
Arthur Douglas Brosius
Michael joseph ruzzio
Kendra Louise Nelson
Gonghua bread
James Alfred Suthers, Jr.
Don Gregory Wishka
Jun Xiao
Application Number:
JP2008546669A
Publication Date:
May 28, 2009
Filing Date:
December 11, 2006
Export Citation:
Assignee:
Pfizer Products Inc.
International Classes:
C07D401/12; A61K31/506; A61P35/00; A61P43/00; C07D487/08; C07D495/08
Attorney, Agent or Firm:
Yoshinobu Murofushi
High Hoji Koji
Junko Miyazawa
Noh four
High Hoji Koji
Junko Miyazawa
Noh four