Title:
ピリジルメチルスルフィニルベンズイミダゾールのための経口速放医薬製剤
Document Type and Number:
Japanese Patent JP2009534441
Kind Code:
A
Abstract:
The invention relates to solid oral pharmaceutical compositions in the form of pellets, mini-tablets, tablets, or capsules, comprising an optionally substituted 2-(pyridylmethylsulfinyl)-1H-benzimidazole, for example esomeprazole, and carrageenan, and optionally one or more excipients. Surprisingly, it has been found that these compositions are stable and rapidly release the active ingredient. The pellets or mini-tablets may be coated as such, or filled in capsules or pressed into tablets, with a polymer, which dissolves only at a pH value of 5 or higher, optionally over a stabilizing intermediate layer.
Inventors:
Leher, marx
Lütorf, Walther
Mark Spitz
Lütorf, Walther
Mark Spitz
Application Number:
JP2009507049A
Publication Date:
September 24, 2009
Filing Date:
April 23, 2007
Export Citation:
Assignee:
MEPHA AG
International Classes:
A61K31/4439; A61K9/16; A61K9/20; A61K9/48; A61K47/36
Domestic Patent References:
| JP2004521955A | 2004-07-22 | |||
| JP2004522796A | 2004-07-29 |
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito
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