Title:
マイクロ粒子およびそれを製造するための方法
Document Type and Number:
Japanese Patent JP2009538926
Kind Code:
A
Abstract:
An active agent and a non-polymeric polyanionic compound are allowed to be associated with a microparticle containing an anionic macromolecule and an anionic polymer in the presence of a crosslink activator. In a non-limiting example, the non-polymeric polyanionic compound is a polyanionic amino acid such as aspartic acid or glutamic acid. The microparticle can be used for modified release of the active agent in vitro and/or in vivo.
Inventors:
Yang, Guohan
Application Number:
JP2009513375A
Publication Date:
November 12, 2009
Filing Date:
May 21, 2007
Export Citation:
Assignee:
BAXTER INTERNATIONAL INCORP0RATED
BAXTER HEALTHCARE S.A.
BAXTER HEALTHCARE S.A.
International Classes:
A61K9/50; A61K47/36; A61K47/42; B01J19/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita