Title:
生体内利用効率の改善されたアミノイソキノリントロンビン阻害薬
Document Type and Number:
Japanese Patent JP2010500321
Kind Code:
A
Abstract:
The invention relates to the compound N-(2-oxo-2-propoxyethyl)-β-phenyl-D-phenyl-alanyl-N-[(1-amino-6-iso-quinolinyl)methyl]-L-prolinamide or a pharmaceutically acceptable salt thereof, to a pharmaceutical composition comprising said compound, as well as to the use of the compound for the manufacture of a medicament for treating or for preventing thrombin mediated diseases.
Inventors:
Robert Gilbert Iran
Bennett, David Jonathan
Bennett, David Jonathan
Application Number:
JP2009523262A
Publication Date:
January 07, 2010
Filing Date:
August 06, 2007
Export Citation:
Assignee:
Narmrose Fuennault Chap Organon
International Classes:
C07K5/078; A61K38/00; A61P7/02; A61P43/00; C12N9/99
Domestic Patent References:
| JP2001523240A | 2001-11-20 | |||
| JPH05155898A | 1993-06-22 | |||
| JPH09500391A | 1997-01-14 | |||
| JP2001523240A | 2001-11-20 | |||
| JPH05155898A | 1993-06-22 | |||
| JPH09500391A | 1997-01-14 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura