Title:
HMW-MAA及びその断片を含む組成物、及びその使用方法
Document Type and Number:
Japanese Patent JP2010500879
Kind Code:
A
Abstract:
A composition comprising a recombinant polypeptide, or a recombinant Listeria strain expressing said recombinant polypeptide, said recombinant polypeptide comprising a fragment of a High Molecular Weight Melanoma-Associated Antigen (HMW-MAA) protein encoded by a nucleotide sequence selected from SEQ ID NOs: 21-23, and a PEST sequence from Listeria, for use in preventing or inhibiting a tumor growth or cancer in a subject.
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Inventors:
Paterson, Yvonne
Machiag, Paul
Ferrone, soldano
Machiag, Paul
Ferrone, soldano
Application Number:
JP2009524674A
Publication Date:
January 14, 2010
Filing Date:
August 15, 2007
Export Citation:
Assignee:
The Trustees of the University of Pennsylvania
International Classes:
C12N15/09; A61K39/00; A61P35/00; C07K14/705; C12N1/21
Domestic Patent References:
| JPH11514848A | ||||
| JP2004500405A | 2004-01-08 |
Foreign References:
| WO2006045750A2 | 2006-05-04 |
Other References:
JPN6010044798; Ｉｍｍｕｎｏｌ． Ｒｅｓ．， ２７ ［２-３］ （２００３） ｐ．４５１-４６２
JPN6010044802; Ｊ． Ｉｍｍｕｎｏｌ．， １５６７ ［１１］ （２００１） ｐ．６４７１-６４７９
JPN6010044802; Ｊ． Ｉｍｍｕｎｏｌ．， １５６７ ［１１］ （２００１） ｐ．６４７１-６４７９
Attorney, Agent or Firm:
Yoichi Oshima