Title:
正のアロステリックAMPA受容体モジュレーターを用いて呼吸抑制を阻害する方法
Document Type and Number:
Japanese Patent JP2010501597
Kind Code:
A
Abstract:
The invention is directed to a method for alleviating respiratory depression in a subject as a result of disease of pharmacological agents such as opiates, opioids or barbiturates. The invention also discloses pharmaceutical compositions for use with the method, the composition containing in combination, an analgesic, anaesthetic, or a sedative and a positive allosteric AMPA receptor modulator in an amount sufficient to reduce or inhibit respiratory depression caused by the analgesic, anaesthetic, or sedative.
Inventors:
Joan James, Greer
Application Number:
JP2009525874A
Publication Date:
January 21, 2010
Filing Date:
August 30, 2007
Export Citation:
Assignee:
The Governor's of the University of Alberta
International Classes:
A61K45/00; A61K31/045; A61K31/4468; A61K31/454; A61K31/485; A61K31/515; A61K31/5377; A61K38/22; A61K45/06; A61P11/00; A61P23/00; A61P25/04; A61P25/20
Domestic Patent References:
| JP2003523384A | 2003-08-05 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita