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Title:
置換ピリジルメチルビシクロカルボキサミド化合物
Document Type and Number:
Japanese Patent JP2010503657
Kind Code:
A
Abstract:
This invention relates to novel substituted pyridylmethyl bicyclocarboxamide compounds and to their use in therapy. These compounds are particularly useful as modulators of the VR1 (Type I Vanilloid) receptor, and are thus useful for the treatment of pain, neuralgia, neuropathies, nerve injury, burns, migraine, carpal tunnel syndrome, fibromyalgia, neuritis, sciatica, pelvic hypersensitivity, bladder disease, inflammation, or the like in mammals, especially humans.

Inventors:
Nagayama Satoshi
Yuji Shishido
Hirotaka Tanaka
Application Number:
JP2009527919A
Publication Date:
February 04, 2010
Filing Date:
September 10, 2007
Export Citation:
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Assignee:
Pfizer Japan Inc
International Classes:
C07D213/40; A61K31/44; A61K31/4409; A61K31/4709; A61K45/00; A61P1/02; A61P1/04; A61P1/08; A61P3/04; A61P3/10; A61P9/10; A61P11/00; A61P11/06; A61P11/08; A61P13/02; A61P13/10; A61P13/12; A61P17/02; A61P19/02; A61P21/00; A61P25/00; A61P25/04; A61P25/06; A61P25/28; A61P29/00; A61P29/02; A61P31/18; A61P31/22; A61P35/00; A61P43/00; C07D213/61; C07D401/12
Domestic Patent References:
JPH1180107A1999-03-26
JPH1081664A1998-03-31
Foreign References:
CN1847226A2006-10-18
WO2005070885A12005-08-04
WO2004000785A22003-12-31
Attorney, Agent or Firm:
Yoshinobu Murofushi
High Hoji Koji
Junko Miyazawa
Noh four