Title:
グルコキナーゼ(GLK)活性化剤としてのベンゾイルアミノヘテロシクリル化合物
Document Type and Number:
Japanese Patent JP2010507641
Kind Code:
A
Abstract:
The invention relates to a novel group of compounds of Formula (I) or a salt thereof:
wherein R 1 , R 2 , R 3 , n, A and HET-1 are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK) such as type 2 diabetes. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by GLK using said compounds and methods for preparing compounds of Formula (I).
Inventors:
Martin, Nathaniel George
McCalecher, Darren
Pike, Kurt Gordon
Walling, Michael James
McCalecher, Darren
Pike, Kurt Gordon
Walling, Michael James
Application Number:
JP2009533939A
Publication Date:
March 11, 2010
Filing Date:
October 25, 2007
Export Citation:
Assignee:
AstraZeneca Activrag
International Classes:
C07D241/24; A61K31/4439; A61K31/497; A61P3/04; A61P3/10; A61P43/00; C07D401/12; C07D403/12; C07B61/00
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Naoshi Nakata
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Naoshi Nakata