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Title:
抗再吸収及び骨構築食事サプリメント及び使用方法
Document Type and Number:
Japanese Patent JP2010507669
Kind Code:
A
Abstract:
Disclosed herein are dietary supplement compositions, regimens and methods for increasing or stimulating bone growth, decreasing or preventing bone resorption, increasing bone strength, improving bone structure, and improving bone architecture comprising a first composition comprising a combination of at least two of: quercetin, Siberian ginseng, Sophora japonica , and licorice, wherein the combination of the first composition increases bone morphogenic protein-2 gene, promoter or protein expression; and a second composition comprising an extract of pomegranate in combination with at least one of green tea, grape seed, and ipriflavone, wherein the combination of the second composition inhibits the expression of RANK-L.

Inventors:
Krempin, David W.
Murray, Mary A.
Lynn, Yumei
Guerenbeck, Kevin W.
Da Costa, Sylvia Earl.
Wilkins, Leon M.
Low-Schmidt, Heli
Lana, Jatinder
Revhan, John F.
Fast, David Jay.
Application Number:
JP2009534649A
Publication Date:
March 11, 2010
Filing Date:
October 24, 2007
Export Citation:
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Assignee:
Krempin, Raleigh
Murray, Mary A.
Lynn, Yumei
Guerenbeck, Kevin W.
Da Costa, Sylvia Earl.
Wilkins, Leon M.
Low-Schmidt, Heli
Lana, Jatinder
Revhan, John F.
Fast, David Jay.
International Classes:
A61K31/352; A23L1/30; A23L33/00; A61K36/18; A61K36/25; A61K36/48; A61P19/08; A61P43/00
Domestic Patent References:
JPH07196523A1995-08-01
JP2004507499A2004-03-11
JP2004501201A2004-01-15
JP2000191542A2000-07-11
Foreign References:
US6291533B12001-09-18
WO2001032191A22001-05-10
Other References:
JPN6012047692; J.CELL.BIOCHEM. VOL.92, 2004, P.285-295
JPN6012047693; BULL.EXP.BIOL.MED. VOL.133, NO.3, 2002, P.252-254
JPN6012047694; EUR.J.ORAL SCI. VOL.113, 2005, P.47-52
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei