Title:
ピラゾロ[3,4-d]ピリミジンp38MAPキナーゼインヒビター
Document Type and Number:
Japanese Patent JP2010513370
Kind Code:
A
Abstract:
Compounds of formula Ia or Ib: wherein R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases.
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Inventors:
Gabriel, Tobias
Low, Yen
Low, Yen
Application Number:
JP2009541969A
Publication Date:
April 30, 2010
Filing Date:
December 10, 2007
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D487/04; A61K31/519; A61P1/04; A61P1/16; A61P3/10; A61P7/02; A61P9/04; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/08; A61P17/02; A61P17/06; A61P17/08; A61P19/02; A61P19/06; A61P19/10; A61P21/00; A61P25/00; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/04; A61P31/16; A61P31/18; A61P31/22; A61P33/06; A61P35/00; A61P37/02
Domestic Patent References:
| JP2005537300A | 2005-12-08 | |||
| JP2002517486A | 2002-06-18 | |||
| JP2005531584A | 2005-10-20 |
Foreign References:
| WO2005085248A1 | 2005-09-15 | |||
| WO2005085249A1 | 2005-09-15 |
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito