Title:
絡石藤とイチヤクソウの混合抽出物を含有する炎症性疾患の予防及び/又は治療用医薬組成物
Document Type and Number:
Japanese Patent JP2010516755
Kind Code:
A
Abstract:
The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory diseases comprising a mixture of herbal extracts of Trachelospermi caulis and Pyrola japonica as active ingredients. More particularly, the pharmaceutical composition of the present invention comprises a mixture of herbal extracts of Trachelospermi caulis and Pyrola japonica in a predetermined range thereby exhibiting superior on therapeutic effects for the treatment of pains, acute inflammation, secretion of enzymes associated with factors inducing inflammation, and production of NO, iNOS, etc., as compared to those prepared from single herbal drugs, thus being useful in the prevention and treatment of inflammatory diseases such as arthritis.
Inventors:
Region Min
Hatkyu
Lim Hong
Listen
Lim Jae Yoon
Choi Once
Jun Seung Hoon
Park Ji Hoon
Hatkyu
Lim Hong
Listen
Lim Jae Yoon
Choi Once
Jun Seung Hoon
Park Ji Hoon
Application Number:
JP2009547160A
Publication Date:
May 20, 2010
Filing Date:
December 20, 2007
Export Citation:
Assignee:
Shin-Il Pharmaceutical Company Limited
International Classes:
A61K36/24; A61K36/00; A61K36/18; A61P7/10; A61P19/02; A61P29/00
Domestic Patent References:
| JP2004051616A | 2004-02-19 |
Foreign References:
| CN1813965A | 2006-08-09 | |||
| WO2003000242A2 | 2003-01-03 |
Other References:
JPN6012061008; ＴＡＮ Ｘ-Ｑ ＥＴ ＡＬ: 'Ｂｉｂｌｉｏｇｒａｐｈｉｃ ｄａｔａ： ＸＰ００２５８５４２４ ｜ Ｉｎ ｍｙ ｐａｔｅｎｔｓ ｌｉｓｔ ｜ ＥＰ Ｒｅｇｉｓｔｅｒ ｜ Ｒｅｐｏｒｔ ｄａｔａ ｅｒｒｏｒ ｜ Ｐｒｉｎｔ Ｌｉｇｎａ' Ｐｌａｎｔａ Ｍｅｄｉｃａ Ｖｏｌ．７１，Ｎｏ．１, 2005, ｐｐ．９３-９５
JPN6012061009; ＫＯＳＵＧＥ Ｔ ｅｔ ａｌ: 'ＳＴＵＤＩＥＳ ＯＮ ＢＩＯＡＣＴＩＶＥ ＳＵＢＳＴＡＮＣＥＳ ＩＮ ＴＨＥ ＣＨＩＮＥＳＥ ＭＡＴＥＲＩＡＬ ＭＥＤＩＣＩＮＥＳ． ＵＳＥＤＦＯＲ ＡＲＴＨＲＩＴＩＣ ＤＩＳＥＡＳＥＳ ＩＮ ＴＲＡ' ＹＡＫＵＧＡＫＵ ＺＡＳＳＨＩ １０５ （９）, 1985, ｐｐ．８４５-８４７
JPN6012061010; 藤本啓 他: '漢薬・絡石藤に関する研究 （第２報） Ｔｒａｃｈｅｌｏｓｐｅｒｍｕｍ ｊａｓｍｉｎｏｉｄｅｓを基原とする絡石藤の茎部の生理活性成分に' 生薬学雑誌 Ｖｏｌ．４６，Ｎｏ．３, 1992, Ｐａｇｅ．２２４-２２９
JPN6012061011; ＫＩＭ Ｊ Ｓ ＥＴ ＡＬ: 'Ｐｈｅｎｏｌｉｃ ｇｌｙｃｏｓｉｄｅｓ ｆｒｏｍ Ｐｙｒｏｌａ ｊａｐｏｎｉｃａ' ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ Ｖｏｌ．５２，Ｎｏ．６, 2004, ｐｐ．７１４-７１７
JPN6012061012; ＬＥＥ ＳＡＮＧＭＹＵＮＧ ＥＴ ＡＬ: 'Ａ ｎｅｗ ｎａｐｈｔｈｏｑｕｉｎｏｎｅ ｆｒｏｍ Ｐｙｒｏｌａ ｊａｐｏｎｉｃａ' ＡＲＣＨＩＶＥＳ ＯＦ ＰＨＡＲＭＡＣＡＬ Ｖｏｌ．２４，Ｎｏ．６, 2001, ｐｐ．５２２-５２３
JPN6012061009; ＫＯＳＵＧＥ Ｔ ｅｔ ａｌ: 'ＳＴＵＤＩＥＳ ＯＮ ＢＩＯＡＣＴＩＶＥ ＳＵＢＳＴＡＮＣＥＳ ＩＮ ＴＨＥ ＣＨＩＮＥＳＥ ＭＡＴＥＲＩＡＬ ＭＥＤＩＣＩＮＥＳ． ＵＳＥＤＦＯＲ ＡＲＴＨＲＩＴＩＣ ＤＩＳＥＡＳＥＳ ＩＮ ＴＲＡ' ＹＡＫＵＧＡＫＵ ＺＡＳＳＨＩ １０５ （９）, 1985, ｐｐ．８４５-８４７
JPN6012061010; 藤本啓 他: '漢薬・絡石藤に関する研究 （第２報） Ｔｒａｃｈｅｌｏｓｐｅｒｍｕｍ ｊａｓｍｉｎｏｉｄｅｓを基原とする絡石藤の茎部の生理活性成分に' 生薬学雑誌 Ｖｏｌ．４６，Ｎｏ．３, 1992, Ｐａｇｅ．２２４-２２９
JPN6012061011; ＫＩＭ Ｊ Ｓ ＥＴ ＡＬ: 'Ｐｈｅｎｏｌｉｃ ｇｌｙｃｏｓｉｄｅｓ ｆｒｏｍ Ｐｙｒｏｌａ ｊａｐｏｎｉｃａ' ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ Ｖｏｌ．５２，Ｎｏ．６, 2004, ｐｐ．７１４-７１７
JPN6012061012; ＬＥＥ ＳＡＮＧＭＹＵＮＧ ＥＴ ＡＬ: 'Ａ ｎｅｗ ｎａｐｈｔｈｏｑｕｉｎｏｎｅ ｆｒｏｍ Ｐｙｒｏｌａ ｊａｐｏｎｉｃａ' ＡＲＣＨＩＶＥＳ ＯＦ ＰＨＡＲＭＡＣＡＬ Ｖｏｌ．２４，Ｎｏ．６, 2001, ｐｐ．５２２-５２３
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki