Title:
改善されたファージ耐性をもつ培養物
Document Type and Number:
Japanese Patent JP2010519929
Kind Code:
A
Abstract:
The present invention provides methods and compositions related to modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some preferred embodiments, the present invention provides compositions and methods for the use of one or more cas genes or proteins for modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some embodiments, the present invention provides methods and compositions that find use in the development and use of strain combinations and starter culture rotations. In additional embodiments, the present invention provides methods for labelling and/or identifying bacteria. In some preferred embodiments, the present invention provides methods for the use of CRISPR loci to determine the potential virulence of a phage against a cell and the use of CRISPR-cas to modulate the genetic sequence of a phage for increased virulence level. In still further embodiments, the present invention provides means and compositions for the development and use of phages as biocontrol agents.
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Inventors:
Barlangou, Rodolph
Flemaux, Christoph
Hovath, Philip
Romero and Dennis
Voyaval, Patrick
Flemaux, Christoph
Hovath, Philip
Romero and Dennis
Voyaval, Patrick
Application Number:
JP2009552701A
Publication Date:
June 10, 2010
Filing Date:
February 29, 2008
Export Citation:
Assignee:
Danisco A.S.
International Classes:
C12N15/09; A23K20/195; C12N1/02; C12Q1/68
Foreign References:
| WO2007025097A2 | 2007-03-01 | |||
| WO2007025097A2 | 2007-03-01 |
Other References:
JPN6012023717; Ｍｉｃｒｏｂｉｏｌｏｇｙ ｖｏｌ．１５１， ｎｏ．８, 2005, ｐｐ．２５５１-２５６１
JPN6012023719; ＰＬｏＳ Ｃｏｍｐｕｔ． Ｂｉｏｌ． ｖｏｌ．１， ｎｏ．６, 2005, ｐｐ．０４７４-０４８３
JPN6012023721; Ｊ． Ｍｏｌ． Ｅｖｏｌ． ｖｏｌ．６０， ｎｏ．２, 2005, ｐｐ．１７４-１８２
JPN6014053559; Ｊ Ｆｏｏｄ Ｐｒｏｔ． １９９７， ６０（１）， ｐ．５９-６３ , 1997
JPN6014053560; Ｉｎｔ Ｊ Ｆｏｏｄ Ｍｉｃｒｏｂｉｏｌ． ２００３， ８６（３）， ｐ．２１３-２２ , 2003
JPN6012023719; ＰＬｏＳ Ｃｏｍｐｕｔ． Ｂｉｏｌ． ｖｏｌ．１， ｎｏ．６, 2005, ｐｐ．０４７４-０４８３
JPN6012023721; Ｊ． Ｍｏｌ． Ｅｖｏｌ． ｖｏｌ．６０， ｎｏ．２, 2005, ｐｐ．１７４-１８２
JPN6014053559; Ｊ Ｆｏｏｄ Ｐｒｏｔ． １９９７， ６０（１）， ｐ．５９-６３ , 1997
JPN6014053560; Ｉｎｔ Ｊ Ｆｏｏｄ Ｍｉｃｒｏｂｉｏｌ． ２００３， ８６（３）， ｐ．２１３-２２ , 2003
Attorney, Agent or Firm:
Yuzo Yamazaki
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ono Wataru
Tadao Naito
Katsuaki Tsunemitsu
Asako Ando
Hirofumi Higashino
Takeko Miko
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ono Wataru
Tadao Naito
Katsuaki Tsunemitsu
Asako Ando
Hirofumi Higashino
Takeko Miko