Title:
炎症の治療に有用な新しいメチレンビスフェニル化合物
Document Type and Number:
Japanese Patent JP2010520268
Kind Code:
A
Abstract:
There is provided compounds of formula (I), wherein Rx, Ry, X1, X2, L1, L2, Y1 and Y2 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
Inventors:
Benjamin Perkman
Peter Nilsson
Peter Nilsson
Application Number:
JP2009552266A
Publication Date:
June 10, 2010
Filing Date:
March 04, 2008
Export Citation:
Assignee:
Biolipox Arb
International Classes:
C07C229/56; A61K31/196; A61K31/245; A61P1/04; A61P1/16; A61P5/24; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P13/10; A61P13/12; A61P17/00; A61P17/04; A61P19/02; A61P25/00; A61P25/04; A61P25/14; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07C227/04; C07C229/58; C07C229/66; C07C273/18; C07C275/42; C07C303/38; C07C311/29; C07C311/41; C07C311/42; C07C311/44
Foreign References:
| WO2003075907A2 | 2003-09-18 | |||
| GB577387B |
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro