Title:
内皮細胞特異性を示すプロモーター及びそのプロモーターを使って血管形成を制御する方法
Document Type and Number:
Japanese Patent JP2010525805
Kind Code:
A
Abstract:
Isolated polynucleotide sequences exhibiting endothelial cell specific promoter activity, novel cis regulatory elements and methods of use thereof enabling treatment of diseases characterized by aberrant neovascularization or cell growth are disclosed.
Inventors:
Braybad, Eyal
Bangio, Rivnut
Haratz, duroll
Pered, michael
Greenberger, Shoshana
Bangio, Rivnut
Haratz, duroll
Pered, michael
Greenberger, Shoshana
Application Number:
JP2010505002A
Publication Date:
July 29, 2010
Filing Date:
April 27, 2008
Export Citation:
Assignee:
Vascular Biogenics Limited
International Classes:
C12N15/09; A61K31/198; A61K31/573; A61K31/7088; A61K35/76; A61K47/20; A61K47/28; A61K48/00; A61P9/10; A61P17/06; A61P27/02; A61P35/00; A61P35/04; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Domestic Patent References:
| JP2005532031A | 2005-10-27 | |||
| JP2004534509A | 2004-11-18 | |||
| JP2005523718A | 2005-08-11 |
Foreign References:
| US20050048466A1 | 2005-03-03 |
Other References:
JPN6013027035; 咽頭 １７, 2005, ８９-９１
JPN6013027036; 日本外科学会雑誌 Ｖｏｌ．１０４ 臨時増刊号, 2003, Ｐａｇｅ．１９１-１９２
JPN6013027039; Ｂｉｏｔｈｅｒａｐｙ ２０（３）, 2006, ｐｐ．２６１-２６９
JPN6013027036; 日本外科学会雑誌 Ｖｏｌ．１０４ 臨時増刊号, 2003, Ｐａｇｅ．１９１-１９２
JPN6013027039; Ｂｉｏｔｈｅｒａｐｙ ２０（３）, 2006, ｐｐ．２６１-２６９
Attorney, Agent or Firm:
Nobuaki Kazehaya
Noriko Asano
Noriko Asano