Title:
糖尿病および代謝疾患の治療のためのRUP3またはGPRl19受容体のアゴニストとしてのN-アザ環状置換ピロール、ピラゾール、イミダゾール、トリアゾールおよびテトラゾール誘導体
Document Type and Number:
Japanese Patent JP2010533721
Kind Code:
A
Abstract:
Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control.
Inventors:
Ma, Ching Yuan
Rabat, Christopher Jay.
Song, Changgao
Chen, Shin
Nashashibi, Imad
Xiao, Tuchung
Novak, Aaron
See, Don Juan
Chain pen
Chu, Yang
Murphy, Allison
Rabat, Christopher Jay.
Song, Changgao
Chen, Shin
Nashashibi, Imad
Xiao, Tuchung
Novak, Aaron
See, Don Juan
Chain pen
Chu, Yang
Murphy, Allison
Application Number:
JP2010517080A
Publication Date:
October 28, 2010
Filing Date:
July 10, 2008
Export Citation:
Assignee:
Metabolex, Incorporated
International Classes:
C07D401/04; A61K31/454; A61K31/4545; A61K31/4709; A61K31/506; A61K31/5377; A61P3/08; A61P3/10; A61P5/50; C07D401/14; C07D413/14; C07D417/14; C07D451/04
Domestic Patent References:
| JP2007533672A | 2007-11-22 | |||
| JP2006518763A | 2006-08-17 | |||
| JP2007045752A | 2007-02-22 | |||
| JPH11513382A | 1999-11-16 | |||
| JPH11500447A | 1999-01-12 | |||
| JP2006525355A | 2006-11-09 | |||
| JP2002514169A | 2002-05-14 | |||
| JP2010526793A | 2010-08-05 | |||
| JP2010530840A | 2010-09-16 |
Foreign References:
| WO2006124692A2 | 2006-11-23 | |||
| WO2004098518A2 | 2004-11-18 | |||
| WO2007014290A2 | 2007-02-01 | |||
| US20050165005A1 | 2005-07-28 | |||
| US5880138A | 1999-03-09 |
Other References:
JPN6013025482; Ｊａｍｅｓ Ｚｈｅｎｇｗｕ Ｄｅｎｇら: Ｔｅｔｒａｈｅｄｒｏｎ Ｌｅｔｔｅｒｓ ４６, 2005, ７９９３-７９９６頁
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita