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Title:
糖尿病および代謝疾患の治療のためのRUP3またはGPRl19受容体のアゴニストとしてのN-アザ環状置換ピロール、ピラゾール、イミダゾール、トリアゾールおよびテトラゾール誘導体
Document Type and Number:
Japanese Patent JP2010533721
Kind Code:
A
Abstract:
Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control.

Inventors:
Ma, Ching Yuan
Rabat, Christopher Jay.
Song, Changgao
Chen, Shin
Nashashibi, Imad
Xiao, Tuchung
Novak, Aaron
See, Don Juan
Chain pen
Chu, Yang
Murphy, Allison
Application Number:
JP2010517080A
Publication Date:
October 28, 2010
Filing Date:
July 10, 2008
Export Citation:
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Assignee:
Metabolex, Incorporated
International Classes:
C07D401/04; A61K31/454; A61K31/4545; A61K31/4709; A61K31/506; A61K31/5377; A61P3/08; A61P3/10; A61P5/50; C07D401/14; C07D413/14; C07D417/14; C07D451/04
Domestic Patent References:
JP2007533672A2007-11-22
JP2006518763A2006-08-17
JP2007045752A2007-02-22
JPH11513382A1999-11-16
JPH11500447A1999-01-12
JP2006525355A2006-11-09
JP2002514169A2002-05-14
JP2010526793A2010-08-05
JP2010530840A2010-09-16
Foreign References:
WO2006124692A22006-11-23
WO2004098518A22004-11-18
WO2007014290A22007-02-01
US20050165005A12005-07-28
US5880138A1999-03-09
Other References:
JPN6013025482; James Zhengwu Dengら: Tetrahedron Letters 46, 2005, 7993-7996頁
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita