Title:
呼吸器合胞体ウイルス感染症を治療するための組換え抗体
Document Type and Number:
Japanese Patent JP2010534057
Kind Code:
A
Abstract:
Disclosed are novel polyclonal antibodies, which target respiratory syncytial virus (RSV), as well as novel high affinity antibody molecules reactive with RSV. The polyclonal antibodies may comprise antibody molecules which are reactive with both RSV protein F and RSV protein G, and preferably the polyclonal antibodies target a variety of epitopes on these proteins. The antibody molecules of the invention have shown superior efficacy in vitro and/or in vivo. Also disclosed are methods of producing the antibodies of the invention as well as methods of their use in treatment or prevention of RSV infection.
Inventors:
Johann Land
Henriette Shanning Nielsen
Henriette Shanning Nielsen
Application Number:
JP2009552068A
Publication Date:
November 04, 2010
Filing Date:
March 05, 2008
Export Citation:
Assignee:
SYMPHOGEN A/S
International Classes:
C12N15/09; A61K39/395; A61P31/14; C07K16/10; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Nishino Mitsuru
Fumio Inai
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Nishino Mitsuru
Fumio Inai