Title:
ハロゲン化メチルトランスフェラーゼを発現する組換え型生物を用いた、有機化合物の工業的生産方法
Document Type and Number:
Japanese Patent JP2011505149
Kind Code:
A
Abstract:
The invention relates to a process for production of organic compounds using genetically engineered organisms expressing a S-adenosylmethionine (SAM)-dependent methyl halide transferase and, optionally modified at loci that affect flux through SAM metabolic pathways or affect intracellular halide levels. In one approach the organism, halides (chlorine, bromine and/or iodine); and a carbon source are incubated in a cultivation medium under conditions in which methyl halide is produced. The methyl halide may be collected and converted into non-halogenated organic molecules.
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Inventors:
Voith Christopher A.
Santi Daniel buoy.
Bayer Travis S.
Santi Daniel buoy.
Bayer Travis S.
Application Number:
JP2010536193A
Publication Date:
February 24, 2011
Filing Date:
November 26, 2008
Export Citation:
Assignee:
The Regents of The University of California
Santi Daniel buoy.
Santi Daniel buoy.
International Classes:
C12P5/00; C12N1/13; C12N1/15; C12N1/19; C12N1/21; C12N15/09; C12P1/00
Other References:
JPN6013049025; JOURNAL OF CATALYSIS vol.143, 1993, pp.32-44
JPN6013049027; NATURE vol.315, 1985, pp.55-57
JPN6013049028; Proc. Natl. Acad. Sci. USA vol.95, 1998, pp.12866-12871
JPN6013049022; Proc. Natl. Acad. Sci. USA vol.96, 1999, pp.3611-3615
JPN6013049023; APPLIED AND ENVIRONMENTAL MICROBIOLOGY vol.64 no.8, 1998, pp.2831-2835
JPN6013049024; SCIENCE vol.249, 1990, pp.160-162
JPN6013049027; NATURE vol.315, 1985, pp.55-57
JPN6013049028; Proc. Natl. Acad. Sci. USA vol.95, 1998, pp.12866-12871
JPN6013049022; Proc. Natl. Acad. Sci. USA vol.96, 1999, pp.3611-3615
JPN6013049023; APPLIED AND ENVIRONMENTAL MICROBIOLOGY vol.64 no.8, 1998, pp.2831-2835
JPN6013049024; SCIENCE vol.249, 1990, pp.160-162
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto