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Title:
ハロゲン化メチルトランスフェラーゼを発現する組換え型生物を用いた、有機化合物の工業的生産方法
Document Type and Number:
Japanese Patent JP2011505149
Kind Code:
A
Abstract:
The invention relates to a process for production of organic compounds using genetically engineered organisms expressing a S-adenosylmethionine (SAM)-dependent methyl halide transferase and, optionally modified at loci that affect flux through SAM metabolic pathways or affect intracellular halide levels. In one approach the organism, halides (chlorine, bromine and/or iodine); and a carbon source are incubated in a cultivation medium under conditions in which methyl halide is produced. The methyl halide may be collected and converted into non-halogenated organic molecules.

Inventors:
Voith Christopher A.
Santi Daniel buoy.
Bayer Travis S.
Application Number:
JP2010536193A
Publication Date:
February 24, 2011
Filing Date:
November 26, 2008
Export Citation:
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Assignee:
The Regents of The University of California
Santi Daniel buoy.
International Classes:
C12P5/00; C12N1/13; C12N1/15; C12N1/19; C12N1/21; C12N15/09; C12P1/00
Other References:
JPN6013049025; JOURNAL OF CATALYSIS vol.143, 1993, pp.32-44
JPN6013049027; NATURE vol.315, 1985, pp.55-57
JPN6013049028; Proc. Natl. Acad. Sci. USA vol.95, 1998, pp.12866-12871
JPN6013049022; Proc. Natl. Acad. Sci. USA vol.96, 1999, pp.3611-3615
JPN6013049023; APPLIED AND ENVIRONMENTAL MICROBIOLOGY vol.64 no.8, 1998, pp.2831-2835
JPN6013049024; SCIENCE vol.249, 1990, pp.160-162
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto



 
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