Title:
化学的及びキラル的に純粋なソリフェナシン塩基及びその塩を調製する方法
Document Type and Number:
Japanese Patent JP2011505416
Kind Code:
A
Abstract:
The present invention provides improved processes for preparing chemically and chirally pure Solifenacin base. The present invention also provides for a composition comprising of a salt of Solifenacin having at least 98% purity. The present invention also discloses certain new salts of Solifenacin as well as new polymorphic forms of Solifenacin hydrochloride and Solifenacin oxalate, in pure form.
Inventors:
Dave, Mayank Gunsham Bai
Panday, bipin
Kotari, Himanshuem.
Patel, Pankai Ramanbai
Panday, bipin
Kotari, Himanshuem.
Patel, Pankai Ramanbai
Application Number:
JP2010536587A
Publication Date:
February 24, 2011
Filing Date:
December 02, 2008
Export Citation:
Assignee:
Cadilla health care limited
International Classes:
C07D453/02; A61K31/4725; A61P13/10
Foreign References:
| WO2005105795A1 | 2005-11-10 | |||
| WO2005087231A1 | 2005-09-22 | |||
| WO2007076116A2 | 2007-07-05 | |||
| WO2005075474A1 | 2005-08-18 | |||
| WO1996020194A1 | 1996-07-04 |
Other References:
JPN6012066709; ＮＡＩＴＯ，Ｒ． ｅｔ ａｌ: 'Ｓｙｎｔｈｅｓｉｓ ａｎｄ ａｎｔｉｍｕｓｃａｒｉｎｉｃ ｐｒｏｐｅｒｔｉｅｓ ｏｆ ｑｕｉｎｕｃｌｉｄｉｎ-３-ｙｌ １，２，３，４-ｔｅｔｒａｈｙｄｒｏｉｓｏｑｕｉｎｏｌｉｎｅ-２-ｃａｒｂｏｘｙ' Ｊ Ｍｅｄ Ｃｈｅｍ Ｖｏｌ．４８， Ｎｏ．２１, 2005, ｐ．６５９７-６０６
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei