Title:
骨髄毒性の予測方法
Document Type and Number:
Japanese Patent JP2011512132
Kind Code:
A
Abstract:
The likelihood that a compound will exhibit bone marrow toxicity in an in vivo assay predicted by the ability of the compound to inhibit at least eight kinases from a selected group.
Inventors:
Bitter Hans Marcus Ludwig
Gold stain david michael
Koraja Kyle El.
Lynn Henry
Ola Husky Andrew James
Upal Hardesh
Gold stain david michael
Koraja Kyle El.
Lynn Henry
Ola Husky Andrew James
Upal Hardesh
Application Number:
JP2010546248A
Publication Date:
April 21, 2011
Filing Date:
February 06, 2009
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C12Q1/48; C12N11/00
Domestic Patent References:
| JP2004201574A | 2004-07-22 | |||
| JP2003510093A | 2003-03-18 |
Foreign References:
| WO2001094936A1 | 2001-12-13 |
Other References:
JPN5011007943; ＦＡＢＩＡＮ ＭＩＬＥＳ Ａ: 'Ａ ＳＭＡＬＬ ＭＯＬＥＣＵＬＥ-ＫＩＮＡＳＥ ＩＮＴＥＲＡＣＴＩＯＮ ＭＡＰ ＦＯＲ ＣＬＩＮＩＣＡＬ ＫＩＮＡＳＥ ＩＮＨＩＢＩＴＯＲＳ' ＮＡＴＵＲＥ ＢＩＯＴＥＣＨＮＯＬＯＧＹ Ｖ２３ Ｎ３, 20050301, Ｐ３２９-３３６, ＮＡＴＵＲＥ ＰＵＢＬＩＳＨＩＮＧ ＧＲＯＵＰ
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto