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Title:
ポリペプチドを産生及び分泌させるための構築物及び方法
Document Type and Number:
Japanese Patent JP2011529336
Kind Code:
A
Abstract:
Described herein are molecules, constructs and methods for the production and secretion of polypeptides of interest by host cells, preferably bacterial host cells, and more particularly gram positive bacteria. In particular, the present invention is related to a polynucleic acid encoding a fusion protein and to uses thereof for the secretion of heterologous or homologous polypeptides of interest by a bacterial host cell, preferably Clostridium bacteria. The present invention further relates to methods and constructs for the production and secretion of heterologous or homologous polypeptides of interest proteins by host cells using such polynucleic acids and fusion proteins.

Inventors:
Fierobe, Henry-Pierre
Mingardon, Florence
Chanal-Vial, Angelique
Application Number:
JP2011520518A
Publication Date:
December 08, 2011
Filing Date:
July 30, 2009
Export Citation:
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Assignee:
Total S.A.
Center Nacional Dou la Lucier Siyu Cyantei Fique (Say N Ale S)
UNIVERSITE DE LA MEDITERRANEE
UNIVERSITE DE PROVENCE
El' Institution Nacional de Champs Aprique (ENS A)
International Classes:
C12N15/09; C12N1/21
Other References:
JPN5011010561; MINGARDON F: 'EXPLORATION OF NEW GEOMETRIES IN CELLULOSOME-LIKE CHIMERAS' APPLIED AND ENVIRONMENTAL MICROBIOLOGY V73 N22, 20071101, P7138-7149, AMERICAN SOCIETY FOR MICROBIOLOGY
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Shinobu
Takuya Osugi
Aki Soga
Hirata Midori