化学的ターゲットと特異的に結合する核酸の迅速な確認のための装置

Title:

化学的ターゲットと特異的に結合する核酸の迅速な確認のための装置

Document Type and Number:

Japanese Patent JP2012500009

Kind Code:

A

Abstract:

The present invention relates to microfluidic chips and their use in SELEX. The microfluidic chip preferably includes a reaction chamber that contains a high surface area material that contains target. One preferred high surface area material is a sol-gel derived material. Methods of making the microfluidic chips are described herein, as are uses of these devices to select aptamers against the target.

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Inventors:

Craig Head Harold G.
Squirrel John Tee.
Kim So Young
Paksung Min
Anjiyon
Cho Min Jung

Application Number:

JP2011523219A

Publication Date:

January 05, 2012

Filing Date:

August 17, 2009

Export Citation:

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Assignee:

CORNELL UNIVERSITY
DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
PCL, Inc.

International Classes:

C12M1/00; C12Q1/68; C12N15/09

Domestic Patent References:

JP2007535670A	2007-12-06
JP2006525662A	2006-11-09
JPH05236997A	1993-09-17
JP2007333649A	2007-12-27
JP2003107094A	2003-04-09
JP2007535670A	2007-12-06
JP2006525662A	2006-11-09
JPH05236997A	1993-09-17

Foreign References:

US20080175758A1	2008-07-24
US20040248167A1	2004-12-09
US20080175758A1	2008-07-24

Other References:

JPN6012044239; Ａｎａｌ．　Ｂｉｏａｎａｌ．　Ｃｈｅｍ．Ｖｏｌ．　３８４, 2006, ｐｐ．１９１-１９８
JPN6012044244; Ａｎａｌ．　Ｂｉｏａｎａｌ．　Ｃｈｅｍ．Ｖｏｌ．　３８７, 2007, ｐｐ．１７１-１８２
JPN6012044241; Ａｎａｌ．　Ｃｈｅｍ．Ｖｏｌ．　７８, 2006, ｐｐ．７３９２-７３９６

Attorney, Agent or Firm:

Kenichi Morita
Kenjiro Yamaguchi

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