生体外におけるヒトBリンパ球産生培養システム - The Regents of The University of California

Title:

生体外におけるヒトBリンパ球産生培養システム

Document Type and Number:

Japanese Patent JP2012509666

Kind Code:

A

Abstract:

The present disclosure relates to systems, methods and compositions for the generation of antibody-producing B cells in vitro. Some embodiments are related to an in vitro system for generating antibody-producing B cells from hematopoietic stem/progenitor cells (HSPCs).

Inventors:

Luosin
Yan Lily
David Baltimore

Application Number:

JP2011537633A

Publication Date:

April 26, 2012

Filing Date:

November 19, 2009

Export Citation:

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Assignee:

The Regents of The University of California

International Classes:

C12N5/10; C12N5/00; C12N15/09

Domestic Patent References:

JP2005525800A

2005-09-02

Foreign References:

WO2007134220A2	2007-11-22
US20070116690A1	2007-05-24
WO2007134220A2	2007-11-22
US20070116690A1	2007-05-24

Other References:

JPN6014018362; Ｊｏｈｎｓｏｎ　ｅｔ　ａｌ: Ｔｈｅ　ｊｏｕｒｎａｌ　ｏｆ　ｉｍｍｕｎｏｌｏｇｙＶｏｌ．　１７５, 2005, ｐ．　７３２５-７３３１
JPN6014018367; Ｇｒａｓｓｉｎｇｅｒ　ｅｔ　ａｌ: Ｅｕｒ　Ｊ　ＨａｅｍａｔｏｌＶｏｌ．　７７, 2006, ｐ．　１３４-１４４
JPN6014018370; Ｎｉｓｈｉｈａｒａ　ｅｔ　ａｌ: Ｅｕｒ　Ｊ　ＩｍｍｕｎｏｌＶｏｌ．　２８, 1998, ｐ．　８５５-８６４
JPN6014018373; Ｌｕｏ　ｅｔ　ａｌ: ＢｌｏｏｄＶｏｌ．　１１３，　Ｎｏ．　７, 20081204, ｐ．　１４２２-１４３１
JPN6014018360; Ｆｌｕｃｋｉｇｅｒ　ｅｔ　ａｌ: ＢｌｏｏｄＶＯｌ．　９２，　Ｎｏ．　１２, 19981215, ｐ．　４５０９-４５２０
JPN6014018362; Ｊｏｈｎｓｏｎ　ｅｔ　ａｌ: Ｔｈｅ　ｊｏｕｒｎａｌ　ｏｆ　ｉｍｍｕｎｏｌｏｇｙＶｏｌ．　１７５, 2005, ｐ．　７３２５-７３３１
JPN6014018367; Ｇｒａｓｓｉｎｇｅｒ　ｅｔ　ａｌ: Ｅｕｒ　Ｊ　ＨａｅｍａｔｏｌＶｏｌ．　７７, 2006, ｐ．　１３４-１４４
JPN6014018370; Ｎｉｓｈｉｈａｒａ　ｅｔ　ａｌ: Ｅｕｒ　Ｊ　ＩｍｍｕｎｏｌＶｏｌ．　２８, 1998, ｐ．　８５５-８６４
JPN6014018373; Ｌｕｏ　ｅｔ　ａｌ: ＢｌｏｏｄＶｏｌ．　１１３，　Ｎｏ．　７, 20081204, ｐ．　１４２２-１４３１

Attorney, Agent or Firm:

Kenji Sugimura
Kazuyuki Tomita
Suzuki Kazutoshi

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