Title:
ピロロピラジニル尿素キナーゼ阻害薬
Document Type and Number:
Japanese Patent JP2012510972
Kind Code:
A
Abstract:
The present invention relates to the use of novel pyrrolopyrazinyl urea derivatives of Formula I, wherein the variables R1, R2, R3, R4, and R5 are defined as described herein, which inhibit JAK and are useful for the treatment of auto-immune and inflammatory diseases.
Inventors:
Bamberg, Joe Timothy
Harman, Johannes Cornelius
Remoine, Remy
Sos, Michael
Harman, Johannes Cornelius
Remoine, Remy
Sos, Michael
Application Number:
JP2011538960A
Publication Date:
May 17, 2012
Filing Date:
November 26, 2009
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D487/04; A61K31/4985; A61K31/55; A61P29/00; A61P37/00; A61P43/00
Domestic Patent References:
| JP2010523522A | 2010-07-15 | |||
| JP2004534826A | 2004-11-18 | |||
| JP2003519144A | 2003-06-17 | |||
| JP2008520738A | 2008-06-19 | |||
| JP2008545652A | 2008-12-18 |
Foreign References:
| WO2009106443A1 | 2009-09-03 | |||
| WO2007015866A2 | 2007-02-08 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fusayuki Saito
Fusayuki Saito