Title:
高透過性組成物およびその用途
Document Type and Number:
Japanese Patent JP2012511027
Kind Code:
A
Abstract:
The invention provides compositions or pharmaceutical compositions of novel high penetration compositions (HPC) of a parent compound, which are capable of crossing biological barriers with high penetration efficiency. The HPCs are capable of being converted to parent drugs or parent drug-related compounds such as metabolites after crossing one or more biological barriers and thus can render treatments for the conditions that the parent drugs or parent drug-related compounds can. Additionally, the HPCs are capable of reaching areas that their parent drugs or parent drug-related compounds may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. For example, HPCs of NSAIA have demonstrated indications such as treating hair loss and bold. A HPC can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.
Inventors:
You Chongshi
Application Number:
JP2011539767A
Publication Date:
May 17, 2012
Filing Date:
December 04, 2009
Export Citation:
Assignee:
You Chongshi
International Classes:
A61K31/18; A01N37/12; A01P1/00; A01P3/00; A01P7/04; A61K31/192; A61K31/198; A61K31/22; A61K31/221; A61K31/223; A61K31/232; A61K31/24; A61K31/40; A61K31/404; A61K31/405; A61K31/407; A61K31/415; A61K31/426; A61K31/43; A61K31/4453; A61K31/4462; A61K31/4465; A61K31/454; A61K31/47; A61K31/5375; A61K31/5415; A61K31/545; A61K31/55; A61K31/5575; A61K31/565; A61K31/57; A61K31/64; A61K38/00; A61K38/22; A61P1/16; A61P1/18; A61P3/10; A61P5/14; A61P9/00; A61P9/12; A61P11/00; A61P11/14; A61P15/04; A61P15/18; A61P17/00; A61P17/10; A61P17/14; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P27/06; A61P27/12; A61P31/04; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P43/00; C07C219/06; C07C219/14; C07C229/36; C07C233/47; C07C233/54; C07C233/83; C07C311/41; C07C403/12; C07C403/20; C07C405/00; C07D207/337; C07D209/26; C07D211/22; C07D215/18; C07D231/12; C07D277/20; C07D277/30; C07D295/08; C07D313/14; C07D337/14; C07D417/04; C07D491/052; C07D499/21; C07D501/60; C07J41/00
Foreign References:
| WO2008093173A1 | 2008-08-07 | |||
| WO2008020270A1 | 2008-02-21 | |||
| WO2008029200A1 | 2008-03-13 | |||
| WO2008007171A1 | 2008-01-17 |
Other References:
JPN6014005909; ＨＯＶＧＡＡＲＤ，Ｌ． ｅｔ ａｌ: Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｒｅｓｅａｒｃｈ Ｖｏｌ．１２， Ｎｏ．３, 1995, ｐ．３８７-３９２
JPN6014005911; 小田切 優樹 他: 'プロドラッグ' 新・ドラッグデリバリーシステム , 20000131, ｐ．１２３-１３５, 株式会社シーエムシー
CSNC200900984013; 小田切 優樹 他: 'プロドラッグ' 新・ドラッグデリバリーシステム , 20000131, ｐ．１２３-１３５, 株式会社シーエムシー
JPN6014005911; 小田切 優樹 他: 'プロドラッグ' 新・ドラッグデリバリーシステム , 20000131, ｐ．１２３-１３５, 株式会社シーエムシー
CSNC200900984013; 小田切 優樹 他: 'プロドラッグ' 新・ドラッグデリバリーシステム , 20000131, ｐ．１２３-１３５, 株式会社シーエムシー
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Shimura
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Shimura