常磁性-イノシトールフォスフェート複合体を用いた磁気共鳴映像用造影剤 - Gachon University of Medicine and Science Industry Academic Co-operation Foundation

Title:

常磁性-イノシトールフォスフェート複合体を用いた磁気共鳴映像用造影剤

Document Type and Number:

Japanese Patent JP2012520871

Kind Code:

A

Abstract:

Disclosed are novel MRI contrast agents and imaging methods using the same. The novel MRI contrast agent comprises a chelating molecule with at least two phosphate groups coordinated with at least one paramagnetic substances.

Inventors:

Aubun Tur
Kim Hyun Jin

Application Number:

JP2012500707A

Publication Date:

September 10, 2012

Filing Date:

January 05, 2010

Export Citation:

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Assignee:

Gachon University of Medicine and Science Industry Academic Co-operation Foundation

International Classes:

A61K49/00; A61B5/055

Domestic Patent References:

JPH04225925A

1992-08-14

Foreign References:

WO1989000052A1

1989-01-12

Other References:

JPN6013020082; Ｒａｄｉｏｌｏｇｙ　ＦｒｏｎｔｉｅｒＶｏｌ．９　Ｎｏ．４, 2006, ｐｐ．２６１-２６９
JPN7013001555; ＵＮＧＥＲ，Ｅ．Ｃ．　ｅｔ　ａｌ: 'Ｐｒｅｌｉｍｉｎａｒｙ　ｅｖａｌｕａｔｉｏｎ　ｏｆ　ｉｒｏｎ　ｐｈｙｔａｔｅ　（ｉｎｏｓｉｔｏｌ　ｈｅｘａｐｈｏｓｐｈａｔｅ）　ａｓ　ａ　ｇａｓｔｒｏｉｎｔｅｓｔｉｎａｌ　ＭＲ　ｃｏｎｔｒａｓｔ　ａｇ' Ｊ　Ｍａｇｎ　Ｒｅｓｏｎ　ＩｍａｇｉｎｇＶｏｌ．３，　Ｎｏ．１, 1993, ｐ．１１９-２４
JPN6013020080; ＩＭＡＮＩＳＨＩ，Ｙ．　ｅｔ　ａｌ: 'Ａ　ｒａｒｅ　ｐｏｒｔｏｓｙｓｔｅｍｉｃ　ｓｈｕｎｔ　ｄｅｔｅｃｔｅｄ　ｂｙ　ＭＲＩ　ａｎｄ　ｄｉａｇｎｏｓｅｄ　ｂｙ　ｄｙｎａｍｉｃ　ｌｉｖｅｒ　ｓｃｉｎｔｉｇｒａｐｈｙ　ｗｉｔｈ　Ｔｃ-９９ｍ　ｐ' Ｃｌｉｎ　Ｎｕｃｌ　ＭｅｄＶｏｌ．１９，　Ｎｏ．４, 1994, ｐ．３２１-４
JPN6013020082; 'ＣＴ，　ＭＲＩによる消化器癌リンパ節の画像診断' Ｒａｄｉｏｌｏｇｙ　ＦｒｏｎｔｉｅｒＶｏｌ．９，　ｎｏ．４, 2006, ｐ．２６１-２６９
JPN6014049570; Ｉｎｏｒｇａｎｉｃａ　Ｃｈｉｍ．　ＡｃｔａＶｏｌ．１４０, 1987, ｐｐ．３５５-３５７
JPN6014049573; ＡｒｚｎｅｉｍｉｔｔｅｌｆｏｒｓｃｈｕｎｇＶｏｌ．４０　Ｎｏ．７, 1990, ｐｐ．７５４-７６０
JPN6014049575; ＲａｄｉｏｉｓｏｔｏｐｅｓＶｏｌ．２４　Ｎｏ．１, 1975, ｐｐ．３１-３５

Attorney, Agent or Firm:

Takeshi Sekine
Atsushi Watanabe

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