Title:
HSP90阻害剤としてのレゾルシノール誘導体
Document Type and Number:
Japanese Patent JP2012524743
Kind Code:
A
Abstract:
The present invention relates to substituted resorcinol derivatives which inhibit the activity of Heat Shock Protein HSP90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, pharmaceutical compositions comprising them, methods of treating diseases and the pharmaceutical compositions comprising these compounds.
Inventors:
Blasca, Maria Gabriella
Casale, Elena
Farugasson, Ron
Portucci, Paolo
Zukkotto, Huavio
Casale, Elena
Farugasson, Ron
Portucci, Paolo
Zukkotto, Huavio
Application Number:
JP2012506450A
Publication Date:
October 18, 2012
Filing Date:
April 16, 2010
Export Citation:
Assignee:
Nerbiano Medieval Sciences Etse Erle Erle
International Classes:
C07D261/14; A61K31/415; A61K31/42; A61K31/439; A61K31/454; A61K31/4545; A61K31/496; A61K31/5377; A61P25/28; A61P35/00; C07D231/14; C07D261/18; C07D277/20; C07D277/56; C07D407/14; C07D413/12; C07D413/14; C07D453/02; C12N9/99
Foreign References:
| WO2004072051A1 | 2004-08-26 | |||
| WO2003053368A2 | 2003-07-03 | |||
| WO2008097640A2 | 2008-08-14 |
Other References:
JPN5012012364; ＢＲＯＵＧＨ Ｐ Ａ: ＪＯＵＲＮＡＬ ＯＦ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ Ｖ５１ Ｎ２, 20071120, Ｐ１９６-２１８, ＡＭＥＲＩＣＡＮ ＣＨＥＭＩＣＡＬ ＳＯＣＩＥＴＹ
Attorney, Agent or Firm:
Kawaguchi International Patent Office