Title:
BACE2インヒビターとしての使用のためのジヒドロピリミジノン
Document Type and Number:
Japanese Patent JP2012526076
Kind Code:
A
Abstract:
This invention relates to dihydropyrimidinones of the formula wherein X and R1 to R7 are as defined in the description, as well as pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors and can be used as medicaments for the treatment or prevention of diseases such as diabetes.
Inventors:
Banner, david
Hilpelt, Hans
Hum, roland
Mouser, halalt
Myvek, alexander fao
Ricklin, Fabian
Rogers-Evans, Mark
Hilpelt, Hans
Hum, roland
Mouser, halalt
Myvek, alexander fao
Ricklin, Fabian
Rogers-Evans, Mark
Application Number:
JP2012509018A
Publication Date:
October 25, 2012
Filing Date:
May 05, 2010
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D239/22; A61K31/513; A61K31/517; A61P3/10; A61P43/00; C07D239/30; C07D401/12; C07D403/12; C07D409/12; C07D413/12; C07D417/12; C07D471/04; C07D495/04
Foreign References:
| WO2006041404A1 | 2006-04-20 | |||
| WO2006041405A1 | 2006-04-20 | |||
| WO2006009653A1 | 2006-01-26 | |||
| WO2007016012A2 | 2007-02-08 | |||
| WO2007073284A1 | 2007-06-28 | |||
| WO2010047372A1 | 2010-04-29 | |||
| WO2006041404A1 | 2006-04-20 | |||
| WO2006041405A1 | 2006-04-20 | |||
| WO2006009653A1 | 2006-01-26 | |||
| WO2007016012A2 | 2007-02-08 | |||
| WO2007073284A1 | 2007-06-28 |
Attorney, Agent or Firm:
Hajime Tsukuni
Satoko Ito
Keiko Ozawa
Satoko Ito
Keiko Ozawa