Title:
タンパク質キナーゼ調節剤としてのピリジンおよびピラジン誘導体
Document Type and Number:
Japanese Patent JP2013500311
Kind Code:
A
Abstract:
The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
Inventors:
Paul A. Versanti
Fu Chen
Jeff Gin
Robert Keith
Robert Kuseko
Xiao Dong Lin
Bread Yue
Keith Be Pfister
Martin Zentzig
James Sutton
One Rifen
Fu Chen
Jeff Gin
Robert Keith
Robert Kuseko
Xiao Dong Lin
Bread Yue
Keith Be Pfister
Martin Zentzig
James Sutton
One Rifen
Application Number:
JP2012522168A
Publication Date:
January 07, 2013
Filing Date:
July 28, 2010
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D213/38; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61P1/00; A61P1/18; A61P9/00; A61P11/00; A61P13/10; A61P15/00; A61P19/00; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P43/00; C07D401/04; C07D401/14; C07D405/14; C07D409/14; C07D413/14
Domestic Patent References:
| JP2005530760A | 2005-10-13 | |||
| JP2011520887A | 2011-07-21 | |||
| JP2012512906A | 2012-06-07 | |||
| JP2004523474A | 2004-08-05 | |||
| JP2007532669A | 2007-11-15 | |||
| JPH0995489A | 1997-04-08 |
Foreign References:
| WO2008079933A2 | 2008-07-03 | |||
| WO2004009562A1 | 2004-01-29 | |||
| DE4031798A1 | 1992-04-09 |
Other References:
CHEM. COMMUN., JPN6013055183, 1996, pages 81 - 83, ISSN: 0002674772
J. MED. CHEM., vol. 48, JPN6013055175, 2005, pages 1886 - 1900, ISSN: 0002674769
EUR. J. ORG. CHEM., JPN6013055178, 1998, pages 2907 - 2912, ISSN: 0002674770
J. MED. CHEM., vol. 48, JPN6013055180, 2005, pages 4535 - 4546, ISSN: 0002674771
J. MED. CHEM., vol. 48, JPN6013055175, 2005, pages 1886 - 1900, ISSN: 0002674769
EUR. J. ORG. CHEM., JPN6013055178, 1998, pages 2907 - 2912, ISSN: 0002674770
J. MED. CHEM., vol. 48, JPN6013055180, 2005, pages 4535 - 4546, ISSN: 0002674771
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai