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Title:
新規タンパク質
Document Type and Number:
Japanese Patent JP2013500739
Kind Code:
A
Abstract:
Provided herein are four polypeptides, named PRT5, PRT6, PRT7 and PRT8, the nucleic acids encoding the same, compositions comprising the proteins, as well as their uses in therapeutic and diagnostic methods. Antibodies which specifically recognize the polypeptides are also provided, as well as their uses. Characterization of each protein showed that PRT5 and PRT8 are involved in glucose metabolism, PRT6 is involved in androgen regulation, while PRT7 correlates with cancer.

Inventors:
Sandler, Tamara
Debury, Orly
Application Number:
JP2012523432A
Publication Date:
January 10, 2013
Filing Date:
August 02, 2010
Export Citation:
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Assignee:
Two to Biotech Limited
International Classes:
C12N15/09; A61K38/00; A61K48/00; A61P3/04; A61P3/06; A61P3/10; A61P5/26; A61P15/08; A61P29/00; A61P31/00; A61P35/00; A61P37/06; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; G01N33/53; G01N33/574; C12P21/08
Other References:
JPN6014047839; Obes. Rev. Vol.6, No.1, 2005, pp.13-21
JPN6014047834; Diabetes Vol.46, No.1, 1997, pp.11-16
JPN6014047839; Obes. Rev. Vol.6, No.1, 2005, pp.13-21
JPN6014047834; Diabetes Vol.46, No.1, 1997, pp.11-16
JPN6014047835; Biochem. J. Vol.357, Pt.1, 2001, pp.127-135
JPN6014047837; Diabetologia Vol.48, No.1, 2005, pp.132-139
JPN6014047835; Biochem. J. Vol.357, Pt.1, 2001, pp.127-135
JPN6014047837; Diabetologia Vol.48, No.1, 2005, pp.132-139
Attorney, Agent or Firm:
Asamura patent office
Hideto Asamura
Hajime Asamura
Shinichi Inoue
Naganuma Akio