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Title:
分子インプリントポリマー、それらを製造するための方法およびそれらの使用
Document Type and Number:
Japanese Patent JP2013501108
Kind Code:
A
Abstract:
The present invention relates to methods of preparing molecularly imprinted polymers (MIPs) which facilitate chemical hydrolysis and more particularly the hydrolysis of chemical substrates which possess hydrolytically labile bonds such as peptides and proteins. The present invention is thus directed to MIPs designed to possess hydrolytic activity, methods for preparing such MIPs and uses of the MIPs.

Inventors:
Milton Tidwell Hahn
Jamil M Choudori
Reinhard Ingemer Boysen
Idida Be Banti
Application Number:
JP2012523168A
Publication Date:
January 10, 2013
Filing Date:
August 05, 2010
Export Citation:
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Assignee:
Monash University
International Classes:
C08F2/44; C08F226/06
Domestic Patent References:
JP2003326172A2003-11-18
JP2003520843A2003-07-08
JP2009515696A2009-04-16
Foreign References:
WO2007096135A12007-08-30
WO2007023915A12007-03-01
US5110833A1992-05-05
Other References:
JPN6014008234; SELLERGREN, B. ET AL.: 'Enantioselective ester hydrolysis catalyzed by imprinted polymers. 2' JOURNAL OF ORGANIC CHEMISTRY vol. 65, 2000, pages 4009-4027
JPN6014008235; WULFF, G. ET AL.: 'Enzyme models based on molecularly imprinted polymers with strong esterase activity' ANGEW. CHEM. INT. ED. ENGL. vol. 36, no. 18, 1997, pages 1961-1964
JPN6014008237; CHEN, W. ET AL.: 'Molecularly imprinted polymers having amidine and imidazole functional groups as an enzyme-mimetic c' MACROMOLECULAR RESEARCH vol. 10, no. 2, 2002, pages 122-126
JPN6014008238; LELE, B. S. ET AL.: 'Molecularly imprinted polymer mimics of chymotrypsin 1. Cooperative effects and substrate specificit' REACTIVE AND FUNCTIONAL POLYMERS vol. 39, 1999, pages 37-52
JPN6014008240; LELE, B. S. ET AL.: 'Molecularly.imprinted polymer mimics of chymotrypsin 2. Functional monomers and hydrolytic activity' REACTIVE AND FUNCTIONAL POLYMERS vol. 40, 1999, pages 215-229
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro