Title:
マクロファージ刺激タンパク質のヘプシン活性化を調節するための方法及び組成物
Document Type and Number:
Japanese Patent JP2013507967
Kind Code:
A
Abstract:
The invention provides methods and compositions for modulating hepsin activity and the MSP/Ron pathway, in particular by regulating pro-MSP activation by hepsin.
Inventors:
Ganethan, Lakmaar
Kirchhofer, Daniel
Kirchhofer, Daniel
Application Number:
JP2012535380A
Publication Date:
March 07, 2013
Filing Date:
October 21, 2010
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
C12N15/09; A61K38/00; A61K39/395; A61K45/00; A61P35/00; A61P35/02; A61P37/00; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/37
Other References:
JPN6014052864; Ｃａｎｃｅｒ Ｒｅｓ Ｖｏｌ．６６，Ｎｏ．７, 2006, ｐ．３６１１-３６１９
JPN6014052865; Ｊ．Ｍｏｌ．Ｂｉｏｌ． Ｖｏｌ．３４６, 2005, ｐ．１３３５-１３４９
JPN6014052866; ＦＥＢＳ Ｌｅｔｔｅｒｓ Ｖｏｌ．５７９, 2005, ｐ．１９４５-１９５０
JPN6014052867; ＦＥＢＳ Ｊｏｕｒｎａｌ Ｖｏｌ．２７６, 200904, ｐ．２２１３-２２２６
JPN6014052865; Ｊ．Ｍｏｌ．Ｂｉｏｌ． Ｖｏｌ．３４６, 2005, ｐ．１３３５-１３４９
JPN6014052866; ＦＥＢＳ Ｌｅｔｔｅｒｓ Ｖｏｌ．５７９, 2005, ｐ．１９４５-１９５０
JPN6014052867; ＦＥＢＳ Ｊｏｕｒｎａｌ Ｖｏｌ．２７６, 200904, ｐ．２２１３-２２２６
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori