Title:
二層錠製剤
Document Type and Number:
Japanese Patent JP2013510873
Kind Code:
A
Abstract:
The present invention relates to bilayer tablets comprising a metformin hydrochloride formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention further relates to medical uses of said bilayer tablets and to pharmaceutical combinations comprising said bilayer tablets.
Inventors:
Admas Abbe
Kyle Martin
Justin M. Patel
Divyakanto Desai
Peter Timmins
Kyle Martin
Justin M. Patel
Divyakanto Desai
Peter Timmins
Application Number:
JP2012539017A
Publication Date:
March 28, 2013
Filing Date:
November 12, 2010
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
AstraZeneca UK Limited
AstraZeneca UK Limited
International Classes:
A61K31/155; A61K9/24; A61K31/7034; A61K31/7056; A61K45/00; A61K47/02; A61K47/12; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P9/10; A61P9/12; A61P13/12; A61P17/02; A61P25/00; A61P27/02; A61P43/00
Domestic Patent References:
| JP2013506634A | 2013-02-28 | |||
| JP2013510875A | 2013-03-28 | |||
| JP2008517921A | 2008-05-29 | |||
| JP2003144528A | 2003-05-20 | |||
| JP2013506634A | 2013-02-28 | |||
| JP2013510875A | 2013-03-28 |
Foreign References:
| WO2009125975A2 | 2009-10-15 | |||
| WO2008113000A1 | 2008-09-18 |
Other References:
JPN6014045850; Ｃ． Ｊ． Ｂａｉｌｅｙ ｅｔ ａｌ．: Ｄｉａｂｅｔｏｌｏｇｉａ ｖｏｌ．５２， Ｎｏ．Ｓ１, 200910, ｐ．Ｓ７６
JPN6014045852; Ａ． Ｂｏｌｄｙｓ ｅｔ ａｌ．: Ｐｈａｒｍａｃｏｌｏｇｉｃａｌ Ｒｅｐｏｒｔｓ ｖｏｌ．６１， Ｎｏ．５, 200910, ｐ．７７８-７８４
JPN6014045852; Ａ． Ｂｏｌｄｙｓ ｅｔ ａｌ．: Ｐｈａｒｍａｃｏｌｏｇｉｃａｌ Ｒｅｐｏｒｔｓ ｖｏｌ．６１， Ｎｏ．５, 200910, ｐ．７７８-７８４
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto