Title:
二量体IAP阻害剤
Document Type and Number:
Japanese Patent JP2013520466
Kind Code:
A
Abstract:
The present invention provides compounds of formula M-L-M' (where M and M' are each independently a monomeric moiety of Formula (I) and L is a linker). The dimeric compounds have been found to be effective in promoting apoptosis in rapidly dividing cells.
Inventors:
Christopher Shawn Strob
Chen Zhuang
Mark G. Palermo
Chen Zhuang
Mark G. Palermo
Application Number:
JP2012554332A
Publication Date:
June 06, 2013
Filing Date:
February 23, 2011
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K31/337; C07D401/14; A61K31/444; A61P35/00; A61P43/00
Domestic Patent References:
| JP2009545613A | 2009-12-24 | |||
| JP2009512719A | 2009-03-26 |
Foreign References:
| WO2008014236A1 | 2008-01-31 |
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai