Title:
C型肝炎ウィルスNS5Bポリメラーゼの阻害薬
Document Type and Number:
Japanese Patent JP2013521237
Kind Code:
A
Abstract:
Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
Inventors:
McCormus, Casey Quimeron
Riverton, Niger El Jay
Sledge, lithyard
Lee pen
Pen, ciuanjia
Woo, Hao
Nargies, Frank
Haverman, York
Kotsuho, Ube
Liu, silane
Riverton, Niger El Jay
Sledge, lithyard
Lee pen
Pen, ciuanjia
Woo, Hao
Nargies, Frank
Haverman, York
Kotsuho, Ube
Liu, silane
Application Number:
JP2012555284A
Publication Date:
June 10, 2013
Filing Date:
March 02, 2011
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
Merck Sharp & Dohme Corp.
Merck Sharp & Dohme Corp.
International Classes:
C07D307/84; A61K31/343; A61K31/381; A61K31/4025; A61K31/404; A61K31/41; A61K31/4178; A61K31/4184; A61K31/422; A61K31/423; A61K31/4245; A61K31/427; A61K31/428; A61K31/437; A61K31/443; A61K31/4439; A61K31/4725; A61K31/496; A61K31/7056; A61K38/21; A61K45/00; A61P1/16; A61P31/14; A61P43/00; C07D405/12; C07D409/10; C07D413/04; C07D413/14; C07D417/10; C07D471/04; C07D498/04; C07D513/04
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama