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Title:
シアノベンゾチアゾール化合物を使用する生物発光アッセイ
Document Type and Number:
Japanese Patent JP2013521782
Kind Code:
A
Abstract:
The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.

Inventors:
Kelts Jessica
Meisenheimer Poncho
Schultz John
Cali James Jay
Madon Pin
Application Number:
JP2012557289A
Publication Date:
June 13, 2013
Filing Date:
March 11, 2011
Export Citation:
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Assignee:
Promega Corporation
International Classes:
C12Q1/26; C12N9/02
Domestic Patent References:
JP2007091695A2007-04-12
JP2012533654A2012-12-27
JP2007091695A2007-04-12
JP2012533654A2012-12-27
Foreign References:
WO2006130551A22006-12-07
WO2009142678A12009-11-26
WO2006130551A22006-12-07
WO2009142678A12009-11-26
Other References:
JPN6014012006; Zhou et al: ChemBioChem Vol. 9, Issue 5, 20080325, p. 714-718
JPN6014012009; Woodroofe et al: Biochemistry Vol. 47, 20080905, p. 10383-10393
JPN6015019904; Denburg et al: Archives of Biochemistry and Biophysics Vol. 134, 1969, p. 381-394
JPN6014012006; Zhou et al: ChemBioChem Vol. 9, Issue 5, 20080325, p. 714-718
JPN6014012009; Woodroofe et al: Biochemistry Vol. 47, 20080905, p. 10383-10393
JPN6015019904; Denburg et al: Archives of Biochemistry and Biophysics Vol. 134, 1969, p. 381-394
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Takamitsu Hoshino