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Title:
皮膚及び/又は毛髪のライトニング活性物質としてのシクロヘキシルカルバメート化合物
Document Type and Number:
Japanese Patent JP2013526592
Kind Code:
A
Abstract:
The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as skin and/or hair lightening (whitening) actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to novel compounds of formula (I) wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4 -alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR1R2, wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.

Inventors:
Feel Harbor Gabriele
Eltlink Heiko
Titse Nicole
Geman Claudia
Brodhager Rahim
Application Number:
JP2013511543A
Publication Date:
June 24, 2013
Filing Date:
May 25, 2010
Export Citation:
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Assignee:
SIMRISE AG
International Classes:
A61K8/34; A61K8/42; A61K8/49; A61K8/55; A61K8/60; A61K8/67; A61K31/045; A61K31/05; A61K31/27; A61K31/351; A61K31/455; A61K31/6615; A61K31/7034; A61K36/896; A61K45/00; A61K45/06; A61P17/00
Domestic Patent References:
JP2002193726A2002-07-10
JPH06199740A1994-07-19
JP2003535915A2003-12-02
JP2013531629A2013-08-08
JP2013533218A2013-08-22
JP2006511484A2006-04-06
JP2007503392A2007-02-22
JP2004501950A2004-01-22
JP2006523244A2006-10-12
Foreign References:
DE1792331A11971-10-28
US20080255178A12008-10-16
US20030119900A12003-06-26
WO2009144179A12009-12-03
WO1997021678A11997-06-19
Other References:
FRAGRANCE JOURNAL, JPN6013043640, May 2005 (2005-05-01), pages 38 - 42, ISSN: 0002865294
鈴木正人監修, 機能性化粧品III, JPN6012020750, 1 January 2000 (2000-01-01), pages 27 - 35, ISSN: 0002865293
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa