Title:
マトリックスメタロプロテイナーゼ阻害剤
Document Type and Number:
Japanese Patent JP2013538820
Kind Code:
A
Abstract:
The present invention relates to certain sulfone acetic acid derivatives of formula I as MMP inhibitor and processes for its syntheses. The invention also relates to pharmacological compositions containing the compounds of the present invention and methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple scleorisis, gingivitis, atherosclerosis, dry eye, neointimal proliferation which leads to restenosis and ischemic heart failure, stroke, renal disease, tumor metastasis, and other inflammatory disorders characterized by over expression and over activation of a matrix metalloproteinase using the compounds.
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Inventors:
Kera, Manoji Kumar
Satigeli, di tendra
Ny Rajkumar, Yadav
Rauff, Abdul Lehman Abdul
Cliffe, Ian A.
Batnagar, Pradip Kumar
Ray, Abhisit
Shrivastaba, Punit
Dustindal, Snanda Gauche
Satigeli, di tendra
Ny Rajkumar, Yadav
Rauff, Abdul Lehman Abdul
Cliffe, Ian A.
Batnagar, Pradip Kumar
Ray, Abhisit
Shrivastaba, Punit
Dustindal, Snanda Gauche
Application Number:
JP2013529762A
Publication Date:
October 17, 2013
Filing Date:
September 26, 2011
Export Citation:
Assignee:
Ranbaxy Laboratories Limited
International Classes:
C07C323/62; A61K31/192; A61K31/27; A61K45/00; A61P1/02; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P25/00; A61P27/04; A61P29/00; A61P35/04; A61P37/00; C07C315/02; C07C315/04; C07C317/46; C07C317/48; C07C319/20; C07C323/63
Attorney, Agent or Firm:
Hiroe Associates Patent Office