Title:
ヒト上皮成長因子受容体遺伝子内の突然変異を検出するための方法及び組成物
Document Type and Number:
Japanese Patent JP2014500028
Kind Code:
A
Abstract:
The invention comprises reagents and methods for detecting cancer-causing mutations in the human EGFR gene. Further, a method of detecting the mutations and a method of treatment are disclosed.
Inventors:
Keith Bower
Nancy Shane Bruner
Alison Tsang
Nancy Shane Bruner
Alison Tsang
Application Number:
JP2013545098A
Publication Date:
January 09, 2014
Filing Date:
December 17, 2011
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C12N15/09; C12Q1/68
Other References:
JPN6015047435; Ｔｈｅ Ｋｏｒｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｐａｔｈｏｌｏｇｙ， ２００９， Ｖｏｌ．４３， ｐｐ．３８７-３９２
JPN6015047436; Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｏｎｃｏｌｏｇｙ， ２００５， Ｖｏｌ．２３， ｐｐ．２４９３-２５０１
JPN6015047437; Ｏｎｃｏｇｅｎｅ， ２００９， Ｖｏｌ．２８， ｐｐ．Ｓ１４-Ｓ２３
JPN6015047438; Ｎｕｃｌｅｉｃ Ａｃｉｄｓ Ｒｅｓ．， １９８９， Ｖｏｌ．１７， ｐｐ．２５０３-２５１６
JPN6015047439; Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｃａｎｃｅｒ， ２００９， Ｖｏｌ．４５， ｐｐ．１５１８-１５２６
JPN6015047436; Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｏｎｃｏｌｏｇｙ， ２００５， Ｖｏｌ．２３， ｐｐ．２４９３-２５０１
JPN6015047437; Ｏｎｃｏｇｅｎｅ， ２００９， Ｖｏｌ．２８， ｐｐ．Ｓ１４-Ｓ２３
JPN6015047438; Ｎｕｃｌｅｉｃ Ａｃｉｄｓ Ｒｅｓ．， １９８９， Ｖｏｌ．１７， ｐｐ．２５０３-２５１６
JPN6015047439; Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｃａｎｃｅｒ， ２００９， Ｖｏｌ．４５， ｐｐ．１５１８-１５２６
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima