Title:
N置換マンノサミン誘導体、その調製方法及びその使用
Document Type and Number:
Japanese Patent JP2014510781
Kind Code:
A
Abstract:
A compound of the formula (1) wherein R1 is a group removable by hydrogenolysis, and wherein R2 is OH or R2 is —NHR3 wherein R3 is a group removable by hydrogenolysis. The compound can be made from fructose by a Heyns-rearrangement. The compound can be used then to make free D-mannosamine or its salts, D-mannosamine building blocks and mannosamine containing oligo- or polysaccharides, N-acetyl-D-mannosamine and its hydrates and solvates, neuraminic acid derivatives, and viral neuraminidase inhibitors.
Inventors:
Vrasidas, Ioannis
Decane, Jura
Janos, Argnesh
Marathus, Hederos
Lerich, Christoph
Decane, Jura
Janos, Argnesh
Marathus, Hederos
Lerich, Christoph
Application Number:
JP2014504427A
Publication Date:
May 01, 2014
Filing Date:
April 11, 2012
Export Citation:
Assignee:
GLYCOM A/S
International Classes:
C07H15/18; A61K31/351; A61P31/12; A61P43/00; C07D309/28
Attorney, Agent or Firm:
Kishimoto Tatsuto
Akihiko Yamashita
Noriyuki Yamamoto
Akihiko Yamashita
Noriyuki Yamamoto