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Title:
APOE免疫療法
Document Type and Number:
Japanese Patent JP2014511174
Kind Code:
A
Abstract:
The present invention provides antibodies that preferentially bind to an ApoE(1-272) fragment relative to ApoE(1-299). These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of neurological diseases.

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Inventors:
Schenk, Dale, Bee.
Nijar, Tarlochan, Es.
Payne, Philip, W.
Barber, robin
Application Number:
JP2013552736A
Publication Date:
May 15, 2014
Filing Date:
February 07, 2012
Export Citation:
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Assignee:
NEOTOPE BIOSCIENCES LIMITED
International Classes:
C12N15/09; A01K67/027; A61K39/00; A61K39/39; A61K39/395; A61K45/00; A61P25/28; C07K16/18; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/02; C12P21/08; G01N33/15; G01N33/48; G01N33/50
Attorney, Agent or Firm:
sk patent corporation
Akihiko Okuno
Hiroyuki Ito



 
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