RASの調節因子としての水素結合代替大環状分子

Title:

RASの調節因子としての水素結合代替大環状分子

Document Type and Number:

Japanese Patent JP2014513059

Kind Code:

A

Abstract:

The present invention relates to peptides having one or more stable, internally-constrained HBS α-helices, where the peptide is capable of interacting with Ras and related proteins.

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Inventors:

Arora Paramujit
Bar-Hagi Daphna
Pasili Anupam
Yadav Kamlesi

Application Number:

JP2013556666A

Publication Date:

May 29, 2014

Filing Date:

March 02, 2012

Export Citation:

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Assignee:

New York University

International Classes:

C07K14/46; A61K38/00; A61K38/08; A61P35/00; A61P35/02; A61P35/04

Foreign References:

WO2010033879A2

2010-03-25

Other References:

JPN5014004808; ＯＲＧＡＮＩＣ　＆　ＢＩＯＭＯＬＥＣＵＬＡＲ　ＣＨＥＭＩＳＴＲＹＶ８　Ｎ８, 2010, Ｐ１７７３-１７７６
JPN5014004809; ＮＡＴＵＲＥ　ＰＲＯＴＯＣＯＬＳＶ５　Ｎ１１, 2010, Ｐ１８５７-１８６５
JPN5014004808; ＯＲＧＡＮＩＣ　＆　ＢＩＯＭＯＬＥＣＵＬＡＲ　ＣＨＥＭＩＳＴＲＹＶ８　Ｎ８, 2010, Ｐ１７７３-１７７６
JPN5014004809; ＮＡＴＵＲＥ　ＰＲＯＴＯＣＯＬＳＶ５　Ｎ１１, 2010, Ｐ１８５７-１８６５

Attorney, Agent or Firm:

Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto

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