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Title:
酸化窒素放出及びバイオフィルム発達の調節
Document Type and Number:
Japanese Patent JP2014513700
Kind Code:
A
Abstract:
The present invention relates generally to methods and compounds for regulating the release of nitric oxide in the vicinity of biofilm-forming microorganisms to regulate programmed cell death in the microorganisms and thereby promote dispersal of microorganism from biofilms and/or inhibit biofilm formation or development. More particularly, the invention relates to the use of compounds to provide spatial and temporal control over nitric oxide release.

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Inventors:
Barlaud, Nicholas
Kardak, Bharat Gangardal
Kelso, Michael John
Kujerburg, Stafan
Rice, scott
Application Number:
JP2014510613A
Publication Date:
June 05, 2014
Filing Date:
May 16, 2012
Export Citation:
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Assignee:
New South Innovations Pty Limited
University of Wollongong
International Classes:
C07D501/26; A61K31/407; A61K31/496; A61K31/5383; A61K31/545; A61K31/546; A61P9/00; A61P11/00; A61P13/12; A61P27/16; A61P31/04; A61P31/06; A61P43/00; C07D501/34
Foreign References:
DE102007035323A12009-01-29
Other References:
JPN6016002106; Bioorganic & Medicinal Chemistry Letters Vol.13, No.10, 2003, pp.1687-1690
JPN6016002109; Journal of Clinical Microbiology Vol.15, No.5, 1982, pp.954-958
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Ai Fujii
Hidetoshi Hanai